Search results for "Bayesian principal component analysis"

Missing Value Estimation for Microarray Data by Bayesian Principal Component Analysis and Iterative Local Least Squares

2013

Published version of an article from the journal: Mathematical Problems in Engineering. Also available from Hindawi: http://dx.doi.org/10.1155/2013/162938 Missing values are prevalent in microarray data, they course negative influence on downstream microarray analyses, and thus they should be estimated from known values. We propose a BPCA-iLLS method, which is an integration of two commonly used missing value estimation methods-Bayesian principal component analysis (BPCA) and local least squares (LLS). The inferior row-average procedure in LLS is replaced with BPCA, and the least squares method is put into an iterative framework. Comparative result shows that the proposed method has obtaine…